Immunology Notes Dr Najeeb Lectures Pdf New [work] Jun 2026

Triggered by antibody-antigen complexes (specifically IgG or IgM binding to an antigen).

). Characterized by a total lack of functional T and B cells. Requires a bone marrow transplant for survival.

Innate immune cells do not recognize specific specific strains of bacteria; instead, they recognize conserved molecular structures common to broad groups of microbes. immunology notes dr najeeb lectures pdf new

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Activated directly by microbial surface molecules (spontaneous activation). Requires a bone marrow transplant for survival

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Exogenous extracellular antigens (e.g., phagocytosed bacteria)

The most abundant antibody type in serum during a secondary (amnesic) response. It is the only antibody that crosses the placenta to provide passive immunity to the fetus. It also fixes complement and acts as an opsonin.